Not medical advice. Long COVID Commons shares research and community experience for education. No treatment is FDA-approved for long COVID; nothing here recommends a treatment or promises a cure. Talk with your clinician before changing any treatment.
This page lists what researchers are studying, with how many registered long COVID studies on ClinicalTrials.gov mention each one (keyword match on titles and listed interventions, fetched 2026-10-11). A study existing is not evidence that something works, and we make no efficacy claims. See Trials for details.
Medicines being studied
| Being studied | Type | Long COVID studies mentioning it | Open now |
|---|---|---|---|
| Nirmatrelvir-ritonavir (Paxlovid) | Drug | 10 | 3 |
| Cell therapies (stem / cord blood) | Biologic | 9 | 2 |
| Remdesivir | Drug | 3 | 1 |
| Metformin | Drug | 3 | 0 |
| Low-dose naltrexone | Drug | 3 | 1 |
| Ivabradine | Drug | 3 | 0 |
| Amantadine | Drug | 3 | 0 |
| Fluvoxamine | Drug | 3 | 1 |
| JAK inhibitors (baricitinib, abrocitinib) | Drug | 3 | 1 |
| Sirolimus / rapamycin | Drug | 3 | 1 |
| Monoclonal antibodies | Biologic | 3 | 1 |
| Intravenous immunoglobulin (IVIG) | Biologic | 3 | 0 |
| Modafinil / solriamfetol (wakefulness agents) | Drug | 2 | 0 |
| Colchicine | Drug | 2 | 0 |
| Lithium | Drug | 2 | 0 |
| Ensitrelvir | Drug | 1 | 0 |
| Montelukast | Drug | 1 | 1 |
| Vericiguat | Drug | 1 | 0 |
| Maraviroc | Drug | 1 | 1 |
| Antihistamines (H1/H2) | Drug | 1 | 0 |
| Low-dose aripiprazole | Drug | 1 | 1 |
| Ivermectin | Drug | 0 | 0 |
| Guanfacine | Drug | 0 | 0 |
Supplements and nutrition being studied
| Being studied | Type | Long COVID studies mentioning it | Open now |
|---|---|---|---|
| Diet interventions | Diet | 52 | 9 |
| Probiotics / microbiome | Supplement | 12 | 0 |
| Vitamin D | Supplement | 6 | 0 |
| Quercetin / flavonoids | Supplement | 4 | 0 |
| Taurine | Supplement | 3 | 3 |
| Coenzyme Q10 | Supplement | 2 | 1 |
| NAD+ precursors (NR, NMN) | Supplement | 2 | 0 |
| Omega-3 fatty acids | Supplement | 2 | 0 |
| Melatonin | Supplement | 2 | 0 |
| L-arginine / citrulline | Supplement | 1 | 0 |
| N-acetylcysteine | Supplement | 1 | 0 |
| Molecular hydrogen | Supplement | 0 | 0 |
Rehabilitation, devices and other approaches
| Being studied | Type | Long COVID studies mentioning it | Open now |
|---|---|---|---|
| Exercise / rehabilitation | Behavioral | 131 | 13 |
| Breathing / respiratory muscle training | Behavioral | 24 | 5 |
| Psychological therapies (CBT, mindfulness) | Behavioral | 19 | 2 |
| Cognitive training (incl. BrainHQ) | Behavioral | 17 | 2 |
| Vagus nerve stimulation (tVNS) | Device | 14 | 2 |
| Transcranial direct current stimulation (tDCS) | Device | 13 | 1 |
| Acupuncture | Procedure | 9 | 3 |
| Immunoadsorption / apheresis | Procedure | 8 | 2 |
| Hyperbaric oxygen | Procedure | 8 | 2 |
| Stellate ganglion block | Procedure | 5 | 1 |
| Transcranial magnetic stimulation (TMS) | Device | 3 | 2 |
| Pacing / energy management | Behavioral | 3 | 1 |
| Olfactory (smell) training | Behavioral | 3 | 2 |
Counts are approximate (keyword matching) and may include studies that only mention an item.